Skip Navigation Links
 
Text Size
 
 

SIGNS OF TSC (CLINICAL MANIFESTATIONS)

Links to detailed information about each of the manifestations:

First described in the 1880s, tuberous sclerosis complex (TSC), also known as Bourneville's Disease, is a genetic disease that affects multiple organs. It can cause tumors in the skin, kidneys, brain, heart, eyes, lungs, teeth as well as other organ systems.

In most individuals, the disease affects only some of these organs. The severity of TSC can range from mild skin abnormalities to, in severe cases, mental retardation or renal failure. Many TSC manifestations also develop later in life. Most individuals who are mildly affected by TSC lead active and productive lives, but it is important to realize that TSC is a life-long companion and individuals should receive continuous follow-up care.

Due to better testing methods, estimates of TSC frequency have risen dramatically in recent years as individuals with less-severe manifestations of TSC are identified. Population-based studies suggest a prevalence of 1 in 9,407 individuals, but recent estimates place the prevalence to be 1 in 6,000 live births. It is estimated that approximately 50,000 Americans and 1 million individuals worldwide have TSC.


 
  Skip Navigation Links
Find a Local Branch
Find a Global Alliance
Become a Volunteer
Become a Member
Government Outreach
Connect With Others
Ways to Give
Your Impact
 
Make a Donation to the Tuberous Sclerosis Alliance
  calendar
 
 
   



Unlock the Cure: The Tipping Point in the Battle Against TSC
Tuberous Sclerosis Alliance Overview
La Esclerosis Tuberosa (Spanish Intro to TSC)
Infantile Spasms & TSC: A Devastating Diagnosis
Questions & Answers About the TS Alliance


ABOUT TSC
What is TSC?
How is TSC Diagnosed?
Signs of TSC
Genetics of TSC

INDIVIDUALS & FAMILIES
Living with TSC
Family Support
Adult Resources

TSC Connect
Brochures & Booklets
Information Sheets
Life Stages Guides & Personal Journals

Perspective Magazine Archives
TSC Clinics

RESEARCHERS
TS Alliance Grants Program
Other TSC Funding Opportunities
TSC Alert Newsletter Archives
Clinical Trials
TSC Natural History Database
Research Resources
International Scientific Advisory Board

Tuberous Sclerosis Alliance Online CommunityTuberous Sclerosis Alliance Support Community